BDBM50286144 (R)-5-Methyl-3-(tetrahydro-pyridazine-1-carbonyl)-hexanoic acid hydroxyamide::CHEMBL105705

SMILES: CC(C)C[C@H](CC(=O)NO)C(=O)N1CCCCN1

InChI Key: InChIKey=IEHZWPSZVCILAW-SNVBAGLBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-1 (Homo sapiens (Human))	BDBM50286144 ((R)-5-Methyl-3-(tetrahydro-pyridazine-1-carbonyl)-...) Show SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N1CCCCN1 Show InChI InChI=1S/C12H23N3O3/c1-9(2)7-10(8-11(16)14-18)12(17)15-6-4-3-5-13-15/h9-10,13,18H,3-8H2,1-2H3,(H,14,16)/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	9.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-3 (MMP-3)				Bioorg Med Chem Lett 5: 3053-3056 (1995) Article DOI: 10.1016/0960-894X(95)00536-1 BindingDB Entry DOI: 10.7270/Q2GM878P
					More data for this Ligand-Target Pair