null

SMILES: CCOC(=O)C1=C(COCCn2c(C)nc3ccccc23)N=C(C)C([C@H]1c1ccccc1Cl)C(=O)NC(C)(C)C

InChI Key: InChIKey=JDZIZAPLLDXEAZ-SSYAZFEXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50286206 ((R)-5-tert-Butylcarbamoyl-4-(2-chloro-phenyl)-6-me...) Show SMILES CCOC(=O)C1=C(COCCn2c(C)nc3ccccc23)N=C(C)C([C@H]1c1ccccc1Cl)C(=O)NC(C)(C)C |c:5,t:23| Show InChI InChI=1S/C31H37ClN4O4/c1-7-40-30(38)28-24(18-39-17-16-36-20(3)34-23-14-10-11-15-25(23)36)33-19(2)26(29(37)35-31(4,5)6)27(28)21-12-8-9-13-22(21)32/h8-15,26-27H,7,16-18H2,1-6H3,(H,35,37)/t26?,27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory effect on PAF induced platelets aggregation in rabbit				Bioorg Med Chem Lett 5: 3085-3090 (1995) Article DOI: 10.1016/0960-894X(95)00542-7 BindingDB Entry DOI: 10.7270/Q23F4PMW
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50286206 ((R)-5-tert-Butylcarbamoyl-4-(2-chloro-phenyl)-6-me...) Show SMILES CCOC(=O)C1=C(COCCn2c(C)nc3ccccc23)N=C(C)C([C@H]1c1ccccc1Cl)C(=O)NC(C)(C)C |c:5,t:23| Show InChI InChI=1S/C31H37ClN4O4/c1-7-40-30(38)28-24(18-39-17-16-36-20(3)34-23-14-10-11-15-25(23)36)33-19(2)26(29(37)35-31(4,5)6)27(28)21-12-8-9-13-22(21)32/h8-15,26-27H,7,16-18H2,1-6H3,(H,35,37)/t26?,27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory effect on PAF induced platelets aggregation in rabbit				Bioorg Med Chem Lett 5: 3085-3090 (1995) Article DOI: 10.1016/0960-894X(95)00542-7 BindingDB Entry DOI: 10.7270/Q23F4PMW
					More data for this Ligand-Target Pair