BDBM50286212 (R)-4-(2-Chloro-phenyl)-2-methyl-6-[2-(2,4,5-trimethyl-imidazol-1-yl)-ethoxymethyl]-1,4-dihydro-pyridine-3,5-dicarboxylic acid 5-ethyl ester 3-methyl ester::CHEMBL319839

SMILES: CCOC(=O)C1=C(COCCn2c(C)nc(C)c2C)N=C(C)C([C@H]1c1ccccc1Cl)C(=O)OC

InChI Key: InChIKey=RGDJOPXSEHZDCF-OZAIVSQSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286212   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-activating factor receptor (Homo sapiens (Human))	BDBM50286212 ((R)-4-(2-Chloro-phenyl)-2-methyl-6-[2-(2,4,5-trime...) Show SMILES CCOC(=O)C1=C(COCCn2c(C)nc(C)c2C)N=C(C)C([C@H]1c1ccccc1Cl)C(=O)OC |c:5,t:20| Show InChI InChI=1S/C26H32ClN3O5/c1-7-35-26(32)24-21(14-34-13-12-30-17(4)15(2)28-18(30)5)29-16(3)22(25(31)33-6)23(24)19-10-8-9-11-20(19)27/h8-11,22-23H,7,12-14H2,1-6H3/t22?,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory effect on PAF induced platelets aggregation in rabbit				Bioorg Med Chem Lett 5: 3085-3090 (1995) Article DOI: 10.1016/0960-894X(95)00542-7 BindingDB Entry DOI: 10.7270/Q23F4PMW
					More data for this Ligand-Target Pair