BDBM50286432 1-(4-Hydroxy-2-methyl-phenyl)-4-oxo-7-pyridin-4-yl-1,4-dihydro-quinoline-3-carboxylic acid amide::CHEMBL340921

SMILES: Cc1cc(O)ccc1-n1cc(C(N)=O)c(=O)c2ccc(cc12)-c1ccncc1

InChI Key: InChIKey=XOVPCPRZRHQFBI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286432   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calpain1 (Homo sapiens (Human))	BDBM50286432 (1-(4-Hydroxy-2-methyl-phenyl)-4-oxo-7-pyridin-4-yl...) Show SMILES Cc1cc(O)ccc1-n1cc(C(N)=O)c(=O)c2ccc(cc12)-c1ccncc1 Show InChI InChI=1S/C22H17N3O3/c1-13-10-16(26)3-5-19(13)25-12-18(22(23)28)21(27)17-4-2-15(11-20(17)25)14-6-8-24-9-7-14/h2-12,26H,1H3,(H2,23,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against human erythrocyte Calpain 1				Bioorg Med Chem Lett 5: 387-392 (1995) Article DOI: 10.1016/0960-894X(95)00041-Q BindingDB Entry DOI: 10.7270/Q21G0M6W
					More data for this Ligand-Target Pair