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SMILES: Nc1nc(cs1)-c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccccc1

InChI Key: InChIKey=BJERBEHPKAMWQD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50286546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50286546 (4-(3-Benzenesulfonyl-5-chloro-1H-indol-2-yl)-4H-1l...) Show SMILES Nc1nc(cs1)-c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H12ClN3O2S2/c18-10-6-7-13-12(8-10)16(15(20-13)14-9-24-17(19)21-14)25(22,23)11-4-2-1-3-5-11/h1-9,20H,(H2,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	222	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against K103N mutant of HIV-1 reverse transcriptase				Bioorg Med Chem Lett 5: 491-496 (1995) Article DOI: 10.1016/0960-894X(95)00059-3 BindingDB Entry DOI: 10.7270/Q28052KF
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50286546 (4-(3-Benzenesulfonyl-5-chloro-1H-indol-2-yl)-4H-1l...) Show SMILES Nc1nc(cs1)-c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H12ClN3O2S2/c18-10-6-7-13-12(8-10)16(15(20-13)14-9-24-17(19)21-14)25(22,23)11-4-2-1-3-5-11/h1-9,20H,(H2,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against K103N mutant of HIV-1 reverse transcriptase				Bioorg Med Chem Lett 5: 491-496 (1995) Article DOI: 10.1016/0960-894X(95)00059-3 BindingDB Entry DOI: 10.7270/Q28052KF
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1)	BDBM50286546 (4-(3-Benzenesulfonyl-5-chloro-1H-indol-2-yl)-4H-1l...) Show SMILES Nc1nc(cs1)-c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H12ClN3O2S2/c18-10-6-7-13-12(8-10)16(15(20-13)14-9-24-17(19)21-14)25(22,23)11-4-2-1-3-5-11/h1-9,20H,(H2,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 RT with poly.rC-oligo.dG template primer				Bioorg Med Chem Lett 5: 491-496 (1995) Article DOI: 10.1016/0960-894X(95)00059-3 BindingDB Entry DOI: 10.7270/Q28052KF
					More data for this Ligand-Target Pair