BDBM50286673 (2S,2aR)-2-Methoxy-3,3-dioxo-7-phenyl-2,2a,3,4-tetrahydro-6-oxa-3lambda*6*-thia-7b-aza-cyclobuta[e]inden-1-one::CHEMBL349599

SMILES: CO[C@@H]1[C@@H]2N(C1=O)c1c(CS2(=O)=O)coc1-c1ccccc1

InChI Key: InChIKey=YKIQPDMUONAZBW-DZGCQCFKSA-N

Data: 1 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286673   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50286673 ((2S,2aR)-2-Methoxy-3,3-dioxo-7-phenyl-2,2a,3,4-tet...) Show SMILES CO[C@@H]1[C@@H]2N(C1=O)c1c(CS2(=O)=O)coc1-c1ccccc1 Show InChI InChI=1S/C15H13NO5S/c1-20-13-14(17)16-11-10(8-22(18,19)15(13)16)7-21-12(11)9-5-3-2-4-6-9/h2-7,13,15H,8H2,1H3/t13-,15+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against human leukocyte elastase (HLE) expressed as second order inhibition rate constant				Bioorg Med Chem Lett 5: 687-690 (1995) Article DOI: 10.1016/0960-894X(95)00094-A BindingDB Entry DOI: 10.7270/Q2TT4QXN
					More data for this Ligand-Target Pair