BDBM50286894 1-[2-Oxo-1-(2-oxo-2-o-tolyl-ethyl)-5-pyridin-4-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-3-m-tolyl-urea::CHEMBL538912

SMILES: Cc1cccc(NC(=O)NC2N=C(c3ccncc3)c3ccccc3N(CC(=O)c3ccccc3C)C2=O)c1

InChI Key: InChIKey=SRJQZTRUBZDAHV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286894   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CCKBR (RAT)	BDBM50286894 (1-[2-Oxo-1-(2-oxo-2-o-tolyl-ethyl)-5-pyridin-4-yl-...) Show SMILES Cc1cccc(NC(=O)NC2N=C(c3ccncc3)c3ccccc3N(CC(=O)c3ccccc3C)C2=O)c1 |t:11| Show InChI InChI=1S/C31H27N5O3/c1-20-8-7-10-23(18-20)33-31(39)35-29-30(38)36(19-27(37)24-11-4-3-9-21(24)2)26-13-6-5-12-25(26)28(34-29)22-14-16-32-17-15-22/h3-18,29H,19H2,1-2H3,(H2,33,35,39)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards gastrin/Cholecystokinin type B receptor from rat brain using [125I]-CCK-8 as the radioligand				Bioorg Med Chem Lett 6: 55-58 (1996) Article DOI: 10.1016/0960-894X(95)00557-A BindingDB Entry DOI: 10.7270/Q2CJ8DGT
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50286894 (1-[2-Oxo-1-(2-oxo-2-o-tolyl-ethyl)-5-pyridin-4-yl-...) Show SMILES Cc1cccc(NC(=O)NC2N=C(c3ccncc3)c3ccccc3N(CC(=O)c3ccccc3C)C2=O)c1 |t:11| Show InChI InChI=1S/C31H27N5O3/c1-20-8-7-10-23(18-20)33-31(39)35-29-30(38)36(19-27(37)24-11-4-3-9-21(24)2)26-13-6-5-12-25(26)28(34-29)22-14-16-32-17-15-22/h3-18,29H,19H2,1-2H3,(H2,33,35,39)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards Cholecystokinin type A receptor from rat pancreas using [I125]-L-364,718 as the radioligand				Bioorg Med Chem Lett 6: 55-58 (1996) Article DOI: 10.1016/0960-894X(95)00557-A BindingDB Entry DOI: 10.7270/Q2CJ8DGT
					More data for this Ligand-Target Pair