null

SMILES: [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6]=[#6](-[#6](=O)-[#7]-[#6]-[#6]-c1ccccc1)P([#8])([#8])=O

InChI Key: InChIKey=HNGZXDXNPBQYEM-OQAQHVHNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50287116 (((3E,7E)-4,8,12-Trimethyl-1-phenethylcarbamoyl-tri...) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6]=[#6](-[#6](=O)-[#7]-[#6]-[#6]-c1ccccc1)P([#8])([#8])=O |w:14.13| Show InChI InChI=1S/C25H38NO4P/c1-20(2)10-8-11-21(3)12-9-13-22(4)16-17-24(31(28,29)30)25(27)26-19-18-23-14-6-5-7-15-23/h5-7,10,12,14-15,17,22H,8-9,11,13,16,18-19H2,1-4H3,(H,26,27)(H2,28,29,30)/b21-12+,24-17?	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl protein transferase from bovine brain				Bioorg Med Chem Lett 6: 1291-1296 (1996) Article DOI: 10.1016/0960-894X(96)00238-7 BindingDB Entry DOI: 10.7270/Q2ZC82TQ
					More data for this Ligand-Target Pair
Squalene synthase (Rattus norvegicus)	BDBM50287116 (((3E,7E)-4,8,12-Trimethyl-1-phenethylcarbamoyl-tri...) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6]=[#6](-[#6](=O)-[#7]-[#6]-[#6]-c1ccccc1)P([#8])([#8])=O |w:14.13| Show InChI InChI=1S/C25H38NO4P/c1-20(2)10-8-11-21(3)12-9-13-22(4)16-17-24(31(28,29)30)25(27)26-19-18-23-14-6-5-7-15-23/h5-7,10,12,14-15,17,22H,8-9,11,13,16,18-19H2,1-4H3,(H,26,27)(H2,28,29,30)/b21-12+,24-17?	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of squalene synthase from rat liver microsomes				Bioorg Med Chem Lett 6: 1291-1296 (1996) Article DOI: 10.1016/0960-894X(96)00238-7 BindingDB Entry DOI: 10.7270/Q2ZC82TQ
					More data for this Ligand-Target Pair