BDBM50287153 2-(2-Fluoro-benzyl)-1H-indole-5-carboxamidine::CHEMBL27305

SMILES: NC(=N)c1ccc2[nH]c(Cc3ccccc3F)cc2c1

InChI Key: InChIKey=SSFUPAJDVSAUJJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50287153 (2-(2-Fluoro-benzyl)-1H-indole-5-carboxamidine | CH...) Show SMILES NC(=N)c1ccc2[nH]c(Cc3ccccc3F)cc2c1 Show InChI InChI=1S/C16H14FN3/c17-14-4-2-1-3-10(14)8-13-9-12-7-11(16(18)19)5-6-15(12)20-13/h1-7,9,20H,8H2,(H3,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of human alpha-thrombin catalytic activity.				Bioorg Med Chem Lett 6: 1339-1344 (1996) Article DOI: 10.1016/0960-894X(96)00229-6 BindingDB Entry DOI: 10.7270/Q2TM7B2Z
					More data for this Ligand-Target Pair