BDBM50287165 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2-(4-o-tolyl-piperazin-1-yl)-ethyl]-amide::CHEMBL28964

SMILES: COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1C

InChI Key: InChIKey=ZIVBQUNYSGOUKO-UHFFFAOYSA-N

Data: 3 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50287165 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1C Show InChI InChI=1S/C25H28BrN3O2/c1-18-7-3-6-10-23(18)29-15-13-28(14-16-29)12-11-27-25(30)21-17-22(26)19-8-4-5-9-20(19)24(21)31-2/h3-10,17H,11-16H2,1-2H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	63.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Centre for Pharmacy Curated by ChEMBL					Assay Description Competitive inhibition of [3H]spiperone binding to the human dopamine receptor D3 expressed in CHO cells, expressed as 10log Ki				J Med Chem 40: 833-40 (1997) Article DOI: 10.1021/jm9605952 BindingDB Entry DOI: 10.7270/Q23J3F5T
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50287165 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1C Show InChI InChI=1S/C25H28BrN3O2/c1-18-7-3-6-10-23(18)29-15-13-28(14-16-29)12-11-27-25(30)21-17-22(26)19-8-4-5-9-20(19)24(21)31-2/h3-10,17H,11-16H2,1-2H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at Dopamine D3 receptors in rat striatum by [3H]-spiperone displacement.				Bioorg Med Chem Lett 6: 1361-1366 (1996) Article DOI: 10.1016/0960-894X(96)00231-4 BindingDB Entry DOI: 10.7270/Q2PV6K9S
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50287165 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1C Show InChI InChI=1S/C25H28BrN3O2/c1-18-7-3-6-10-23(18)29-15-13-28(14-16-29)12-11-27-25(30)21-17-22(26)19-8-4-5-9-20(19)24(21)31-2/h3-10,17H,11-16H2,1-2H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	484	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at Dopamine D2 receptors in rat striatum by [3H]-spiperone displacement.				Bioorg Med Chem Lett 6: 1361-1366 (1996) Article DOI: 10.1016/0960-894X(96)00231-4 BindingDB Entry DOI: 10.7270/Q2PV6K9S
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50287165 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1C Show InChI InChI=1S/C25H28BrN3O2/c1-18-7-3-6-10-23(18)29-15-13-28(14-16-29)12-11-27-25(30)21-17-22(26)19-8-4-5-9-20(19)24(21)31-2/h3-10,17H,11-16H2,1-2H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for stimulation of mitogenesis in Dopamine receptor D3 transfected CHO p-5 cells				Bioorg Med Chem Lett 6: 1361-1366 (1996) Article DOI: 10.1016/0960-894X(96)00231-4 BindingDB Entry DOI: 10.7270/Q2PV6K9S
					More data for this Ligand-Target Pair