BDBM50287275 2-ammonio-4-[(2-carboxylatobutyl)sulfonyl]butanoate
SMILES: CCC(CS(=O)(=O)CCC([NH3+])C([O-])=O)C([O-])=O
InChI Key: InChIKey=XYMLBPTWMWTSFJ-UHFFFAOYSA-M
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gamma-glutamylcysteine synthetase (Homo sapiens (Human)) | BDBM50287275 (2-ammonio-4-[(2-carboxylatobutyl)sulfonyl]butanoat...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article | 9.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for inhibition of Escherichia coli gamma-glutamylcysteine synthetase at a concentration of 16.3 uM | Bioorg Med Chem Lett 6: 1437-1442 (1996) Article DOI: 10.1016/S0960-894X(96)00247-8 BindingDB Entry DOI: 10.7270/Q2KH0NV4 | |||||||||||
More data for this Ligand-Target Pair |