BDBM50287327 CHEMBL36331::[3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(thiazol-4-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-prop-(E)-ylideneaminooxy]-acetic acid

SMILES: CC(C)(C)Sc1c(CC(C)(C)\C=N\OCC(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3cscn3)cc12

InChI Key: InChIKey=MTOJXLORSZWYNQ-DPNNOFEESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-Lipoxygenase/5-lipoxygenase activating protein (Homo sapiens (Human))	BDBM50287327 (CHEMBL36331 | [3-[3-tert-Butylsulfanyl-1-(4-chloro...) Show SMILES CC(C)(C)Sc1c(CC(C)(C)\C=N\OCC(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3cscn3)cc12 Show InChI InChI=1S/C30H34ClN3O4S2/c1-29(2,3)40-28-24-12-23(37-15-22-17-39-19-32-22)10-11-25(24)34(14-20-6-8-21(31)9-7-20)26(28)13-30(4,5)18-33-38-16-27(35)36/h6-12,17-19H,13-16H2,1-5H3,(H,35,36)/b33-18+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of calcium ionophore (A23187) stimulated LTB4 formation in human neutrophils				Bioorg Med Chem Lett 6: 1547-1552 (1996) Article DOI: 10.1016/S0960-894X(96)00271-5 BindingDB Entry DOI: 10.7270/Q2DF6R6W
					More data for this Ligand-Target Pair
5-Lipoxygenase/5-lipoxygenase activating protein (Homo sapiens (Human))	BDBM50287327 (CHEMBL36331 | [3-[3-tert-Butylsulfanyl-1-(4-chloro...) Show SMILES CC(C)(C)Sc1c(CC(C)(C)\C=N\OCC(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3cscn3)cc12 Show InChI InChI=1S/C30H34ClN3O4S2/c1-29(2,3)40-28-24-12-23(37-15-22-17-39-19-32-22)10-11-25(24)34(14-20-6-8-21(31)9-7-20)26(28)13-30(4,5)18-33-38-16-27(35)36/h6-12,17-19H,13-16H2,1-5H3,(H,35,36)/b33-18+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Human whole blood was stimulated with calcium ionophore (A23187) and LTB 4 measured by enzyme immunoassay				Bioorg Med Chem Lett 6: 1547-1552 (1996) Article DOI: 10.1016/S0960-894X(96)00271-5 BindingDB Entry DOI: 10.7270/Q2DF6R6W
					More data for this Ligand-Target Pair