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SMILES: FC(F)(F)c1cc(CNC(=O)CC(c2ccccc2)c2ccccc2)cc(c1)C(F)(F)F

InChI Key: InChIKey=VAUOHNLMRQQSAZ-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287348   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Substance-P receptor


(Homo sapiens (Human))		BDBM50287348
PNG
(CHEMBL289728 | N-(3,5-Bis-trifluoromethyl-benzyl)-...)
Show SMILES FC(F)(F)c1cc(CNC(=O)CC(c2ccccc2)c2ccccc2)cc(c1)C(F)(F)F
Show InChI InChI=1S/C24H19F6NO/c25-23(26,27)19-11-16(12-20(13-19)24(28,29)30)15-31-22(32)14-21(17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-13,21H,14-15H2,(H,31,32)
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MMDB

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Similars
Article
n/an/a 235n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity for human NK1 receptor determined by displacement of [125I]- Substance P from human NK1 receptor in CHO cells

Bioorg Med Chem Lett 6: 1585-1588 (1996)


Article DOI: 10.1016/S0960-894X(96)00280-6
BindingDB Entry DOI: 10.7270/Q24X57RT
More data for this
Ligand-Target Pair