BDBM50287488 CHEMBL46030::N*4*-Hydroxy-N*1*-[(S)-2-(4-methoxy-phenyl)-1-methylcarbamoyl-ethyl]-2-methyl-2-phenyl-succinamide

SMILES: CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C(C)(CC(=O)NO)c1ccccc1

InChI Key: InChIKey=VFPJVTCOXAYWBO-HXBUSHRASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287488   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50287488 (CHEMBL46030 | N*4*-Hydroxy-N*1*-[(S)-2-(4-methoxy-...) Show SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C(C)(CC(=O)NO)c1ccccc1 Show InChI InChI=1S/C22H27N3O5/c1-22(14-19(26)25-29,16-7-5-4-6-8-16)21(28)24-18(20(27)23-2)13-15-9-11-17(30-3)12-10-15/h4-12,18,29H,13-14H2,1-3H3,(H,23,27)(H,24,28)(H,25,26)/t18-,22?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Matrix Metallo Proteinase-1(MMP-1)				Bioorg Med Chem Lett 6: 1719-1724 (1996) Article DOI: 10.1016/0960-894X(96)00303-4 BindingDB Entry DOI: 10.7270/Q23X86K0
					More data for this Ligand-Target Pair