BDBM50287490 1-Hydroxycarbamoylmethyl-cyclopentanecarboxylic acid [(S)-2-(4-methoxy-phenyl)-1-methylcarbamoyl-ethyl]-amide::CHEMBL299812

SMILES: CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C1(CC(=O)NO)CCCC1

InChI Key: InChIKey=DOCXBWVWGRPLQP-HNNXBMFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287490   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50287490 (1-Hydroxycarbamoylmethyl-cyclopentanecarboxylic ac...) Show SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)C1(CC(=O)NO)CCCC1 Show InChI InChI=1S/C19H27N3O5/c1-20-17(24)15(11-13-5-7-14(27-2)8-6-13)21-18(25)19(9-3-4-10-19)12-16(23)22-26/h5-8,15,26H,3-4,9-12H2,1-2H3,(H,20,24)(H,21,25)(H,22,23)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Matrix Metallo Proteinase-1(MMP-1)				Bioorg Med Chem Lett 6: 1719-1724 (1996) Article DOI: 10.1016/0960-894X(96)00303-4 BindingDB Entry DOI: 10.7270/Q23X86K0
					More data for this Ligand-Target Pair