BDBM50287549 5-(2-(cyclopropylmethoxy)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one::5-(2-Cyclopropylmethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one::CHEMBL52141

SMILES: CCCc1nn(C)c2c1nc([nH]c2=O)-c1ccccc1OCC1CC1

InChI Key: InChIKey=DOEKANBUIKUFKH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287549   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50287549 (5-(2-(cyclopropylmethoxy)phenyl)-1-methyl-3-propyl...) Show SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1ccccc1OCC1CC1 Show InChI InChI=1S/C19H22N4O2/c1-3-6-14-16-17(23(2)22-14)19(24)21-18(20-16)13-7-4-5-8-15(13)25-11-12-9-10-12/h4-5,7-8,12H,3,6,9-11H2,1-2H3,(H,20,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 5 from rabbit platelets				Bioorg Med Chem Lett 6: 1819-1824 (1996) Article DOI: 10.1016/0960-894X(96)00323-X BindingDB Entry DOI: 10.7270/Q2G73DQW
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50287549 (5-(2-(cyclopropylmethoxy)phenyl)-1-methyl-3-propyl...) Show SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1ccccc1OCC1CC1 Show InChI InChI=1S/C19H22N4O2/c1-3-6-14-16-17(23(2)22-14)19(24)21-18(20-16)13-7-4-5-8-15(13)25-11-12-9-10-12/h4-5,7-8,12H,3,6,9-11H2,1-2H3,(H,20,21,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 3 from rabbit platelets				Bioorg Med Chem Lett 6: 1819-1824 (1996) Article DOI: 10.1016/0960-894X(96)00323-X BindingDB Entry DOI: 10.7270/Q2G73DQW
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50287549 (5-(2-(cyclopropylmethoxy)phenyl)-1-methyl-3-propyl...) Show SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1ccccc1OCC1CC1 Show InChI InChI=1S/C19H22N4O2/c1-3-6-14-16-17(23(2)22-14)19(24)21-18(20-16)13-7-4-5-8-15(13)25-11-12-9-10-12/h4-5,7-8,12H,3,6,9-11H2,1-2H3,(H,20,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	955	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Lavras-UFLA Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem 16: 7599-606 (2008) Article DOI: 10.1016/j.bmc.2008.07.022 BindingDB Entry DOI: 10.7270/Q2VX0HRR
					More data for this Ligand-Target Pair