BDBM50287761 5-[1-[4-(4-Benzoyl-benzyloxy)-phenyl]-meth-(Z)-ylidene]-2-thioxo-thiazolidin-4-one::CHEMBL70169

SMILES: SC1=NC(=O)C(S1)=Cc1ccc(OCc2ccc(cc2)C(=O)c2ccccc2)cc1

InChI Key: InChIKey=OGAWSTWAQCJSNJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin D (Homo sapiens (Human))	BDBM50287761 (5-[1-[4-(4-Benzoyl-benzyloxy)-phenyl]-meth-(Z)-yli...) Show SMILES SC1=NC(=O)C(S1)=Cc1ccc(OCc2ccc(cc2)C(=O)c2ccccc2)cc1 |w:7.8,t:1| Show InChI InChI=1S/C24H17NO3S2/c26-22(18-4-2-1-3-5-18)19-10-6-17(7-11-19)15-28-20-12-8-16(9-13-20)14-21-23(27)25-24(29)30-21/h1-14H,15H2,(H,25,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of cathepsin D.				Bioorg Med Chem Lett 6: 2157-2162 (1996) Article DOI: 10.1016/0960-894X(96)00393-9 BindingDB Entry DOI: 10.7270/Q28G8KPZ
					More data for this Ligand-Target Pair