BDBM50288022 CHEMBL310361::N-(4-Bromo-3-methyl-isoxazol-5-yl)-2-fluoro-benzenesulfonamide

SMILES: Cc1noc(NS(=O)(=O)c2ccccc2F)c1Br

InChI Key: InChIKey=ROZIFONKJKKVJE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288022   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EDNRB (Homo sapiens (Human))	BDBM50288022 (CHEMBL310361 | N-(4-Bromo-3-methyl-isoxazol-5-yl)-...) Show SMILES Cc1noc(NS(=O)(=O)c2ccccc2F)c1Br Show InChI InChI=1S/C10H8BrFN2O3S/c1-6-9(11)10(17-13-6)14-18(15,16)8-5-3-2-4-7(8)12/h2-5,14H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against human Endothelin B receptor in transfected COS 7 cell membrane preparation				Bioorg Med Chem Lett 6: 2393-2398 (1996) Article DOI: 10.1016/0960-894X(96)00441-6 BindingDB Entry DOI: 10.7270/Q22V2G3R
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50288022 (CHEMBL310361 | N-(4-Bromo-3-methyl-isoxazol-5-yl)-...) Show SMILES Cc1noc(NS(=O)(=O)c2ccccc2F)c1Br Show InChI InChI=1S/C10H8BrFN2O3S/c1-6-9(11)10(17-13-6)14-18(15,16)8-5-3-2-4-7(8)12/h2-5,14H,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against human Endothelin A receptor in TE 671(ATCC# HTB 139) cell membrane preparation				Bioorg Med Chem Lett 6: 2393-2398 (1996) Article DOI: 10.1016/0960-894X(96)00441-6 BindingDB Entry DOI: 10.7270/Q22V2G3R
					More data for this Ligand-Target Pair