BDBM50288028 CHEMBL78952::N-(3,4-Dimethyl-isoxazol-5-yl)-4-methyl-benzenesulfonamide

SMILES: Cc1noc(NS(=O)(=O)c2ccc(C)cc2)c1C

InChI Key: InChIKey=JGXIRMJIDPMUJD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EDNRB (Homo sapiens (Human))	BDBM50288028 (CHEMBL78952 | N-(3,4-Dimethyl-isoxazol-5-yl)-4-met...) Show SMILES Cc1noc(NS(=O)(=O)c2ccc(C)cc2)c1C Show InChI InChI=1S/C12H14N2O3S/c1-8-4-6-11(7-5-8)18(15,16)14-12-9(2)10(3)13-17-12/h4-7,14H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against human Endothelin B receptor in transfected COS 7 cell membrane preparation				Bioorg Med Chem Lett 6: 2393-2398 (1996) Article DOI: 10.1016/0960-894X(96)00441-6 BindingDB Entry DOI: 10.7270/Q22V2G3R
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50288028 (CHEMBL78952 | N-(3,4-Dimethyl-isoxazol-5-yl)-4-met...) Show SMILES Cc1noc(NS(=O)(=O)c2ccc(C)cc2)c1C Show InChI InChI=1S/C12H14N2O3S/c1-8-4-6-11(7-5-8)18(15,16)14-12-9(2)10(3)13-17-12/h4-7,14H,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against human Endothelin A receptor in TE 671(ATCC# HTB 139) cell membrane preparation				Bioorg Med Chem Lett 6: 2393-2398 (1996) Article DOI: 10.1016/0960-894X(96)00441-6 BindingDB Entry DOI: 10.7270/Q22V2G3R
					More data for this Ligand-Target Pair