BDBM50288041 CHEMBL79080::N-(4-Bromo-3-methyl-isoxazol-5-yl)-4-nitro-benzenesulfonamide

SMILES: Cc1[n-][o+]c(NS(=O)(=O)c2ccc(cc2)[N+]([O-])=O)c1Br

InChI Key: InChIKey=WBNIPOYXTLRYMD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50288041 (CHEMBL79080 | N-(4-Bromo-3-methyl-isoxazol-5-yl)-4...) Show SMILES Cc1[n-][o+]c(NS(=O)(=O)c2ccc(cc2)[N+]([O-])=O)c1Br Show InChI InChI=1S/C10H8BrN3O5S/c1-6-9(11)10(19-12-6)13-20(17,18)8-4-2-7(3-5-8)14(15)16/h2-5,13H,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against human Endothelin A receptor in TE 671(ATCC# HTB 139) cell membrane preparation				Bioorg Med Chem Lett 6: 2393-2398 (1996) Article DOI: 10.1016/0960-894X(96)00441-6 BindingDB Entry DOI: 10.7270/Q22V2G3R
					More data for this Ligand-Target Pair
EDNRB (Homo sapiens (Human))	BDBM50288041 (CHEMBL79080 | N-(4-Bromo-3-methyl-isoxazol-5-yl)-4...) Show SMILES Cc1[n-][o+]c(NS(=O)(=O)c2ccc(cc2)[N+]([O-])=O)c1Br Show InChI InChI=1S/C10H8BrN3O5S/c1-6-9(11)10(19-12-6)13-20(17,18)8-4-2-7(3-5-8)14(15)16/h2-5,13H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against human Endothelin B receptor in transfected COS 7 cell membrane preparation				Bioorg Med Chem Lett 6: 2393-2398 (1996) Article DOI: 10.1016/0960-894X(96)00441-6 BindingDB Entry DOI: 10.7270/Q22V2G3R
					More data for this Ligand-Target Pair