BDBM50288057 3-Carboxy-3-hydroxy-pentanedioic acid mono-[5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,5-dihydro-furan-2-ylmethyl] ester::CHEMBL311770

SMILES: Cc1cn(C2OC(COC(=O)CC(O)(CC(O)=O)C(O)=O)C=C2)c(=O)[nH]c1=O

InChI Key: InChIKey=ORSPRSGGTJQKER-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288057   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50288057 (3-Carboxy-3-hydroxy-pentanedioic acid mono-[5-(5-m...) Show SMILES Cc1cn(C2OC(COC(=O)CC(O)(CC(O)=O)C(O)=O)C=C2)c(=O)[nH]c1=O |c:21| Show InChI InChI=1S/C16H18N2O10/c1-8-6-18(15(25)17-13(8)22)10-3-2-9(28-10)7-27-12(21)5-16(26,14(23)24)4-11(19)20/h2-3,6,9-10,26H,4-5,7H2,1H3,(H,19,20)(H,23,24)(H,17,22,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase.				Bioorg Med Chem Lett 6: 2405-2410 (1996) Article DOI: 10.1016/0960-894X(96)00444-1 BindingDB Entry DOI: 10.7270/Q2Z31ZMC
					More data for this Ligand-Target Pair