BDBM50288059 3-Benzyloxycarbonyl-3-hydroxy-pentanedioic acid benzyl ester 5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,5-dihydro-furan-2-ylmethyl ester::CHEMBL311270

SMILES: Cc1cn(C2OC(COC(=O)CC(O)(CC(=O)OCc3ccccc3)C(=O)OCc3ccccc3)C=C2)c(=O)[nH]c1=O

InChI Key: InChIKey=MQPORVKQALABIR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50288059 (3-Benzyloxycarbonyl-3-hydroxy-pentanedioic acid be...) Show SMILES Cc1cn(C2OC(COC(=O)CC(O)(CC(=O)OCc3ccccc3)C(=O)OCc3ccccc3)C=C2)c(=O)[nH]c1=O |c:37| Show InChI InChI=1S/C30H30N2O10/c1-20-16-32(29(37)31-27(20)35)24-13-12-23(42-24)19-40-26(34)15-30(38,28(36)41-18-22-10-6-3-7-11-22)14-25(33)39-17-21-8-4-2-5-9-21/h2-13,16,23-24,38H,14-15,17-19H2,1H3,(H,31,35,37)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase.				Bioorg Med Chem Lett 6: 2405-2410 (1996) Article DOI: 10.1016/0960-894X(96)00444-1 BindingDB Entry DOI: 10.7270/Q2Z31ZMC
					More data for this Ligand-Target Pair