BDBM50288591 2-(2,3-dihydrobenzo[b]furan-7-ylcarboxamido)-(2S)-4-azabicyclo[2.2.2]octane::CHEMBL91379

SMILES: O=C(N[C@@H]1CN2CCC1CC2)c1cccc2CCOc12

InChI Key: InChIKey=KFFIHMWULIQCHP-CQSZACIVSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50288591   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50288591 (2-(2,3-dihydrobenzo[b]furan-7-ylcarboxamido)-(2S)-...) Show SMILES O=C(N[C@@H]1CN2CCC1CC2)c1cccc2CCOc12 |wU:3.2,(7,-4.89,;8.29,-5.71,;9.67,-4.99,;9.7,-3.44,;11.08,-2.74,;11.15,-1.2,;9.86,-.37,;8.49,-1.1,;8.42,-2.64,;9.22,-1.45,;9.86,-2.1,;8.23,-7.25,;6.86,-7.96,;6.82,-9.51,;8.12,-10.31,;9.47,-9.6,;10.91,-10.15,;11.87,-8.93,;11.02,-7.64,;9.54,-8.07,)| Show InChI InChI=1S/C16H20N2O2/c19-16(13-3-1-2-12-6-9-20-15(12)13)17-14-10-18-7-4-11(14)5-8-18/h1-3,11,14H,4-10H2,(H,17,19)/t14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.				Bioorg Med Chem Lett 6: 263-266 (1996) Article DOI: 10.1016/0960-894X(96)00002-9 BindingDB Entry DOI: 10.7270/Q2MC90JK
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (RAT)	BDBM50288591 (2-(2,3-dihydrobenzo[b]furan-7-ylcarboxamido)-(2S)-...) Show SMILES O=C(N[C@@H]1CN2CCC1CC2)c1cccc2CCOc12 |wU:3.2,(7,-4.89,;8.29,-5.71,;9.67,-4.99,;9.7,-3.44,;11.08,-2.74,;11.15,-1.2,;9.86,-.37,;8.49,-1.1,;8.42,-2.64,;9.22,-1.45,;9.86,-2.1,;8.23,-7.25,;6.86,-7.96,;6.82,-9.51,;8.12,-10.31,;9.47,-9.6,;10.91,-10.15,;11.87,-8.93,;11.02,-7.64,;9.54,-8.07,)| Show InChI InChI=1S/C16H20N2O2/c19-16(13-3-1-2-12-6-9-20-15(12)13)17-14-10-18-7-4-11(14)5-8-18/h1-3,11,14H,4-10H2,(H,17,19)/t14-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatum by [3H]GR-113808 displacement.				Bioorg Med Chem Lett 6: 263-266 (1996) Article DOI: 10.1016/0960-894X(96)00002-9 BindingDB Entry DOI: 10.7270/Q2MC90JK
					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM50288591 (2-(2,3-dihydrobenzo[b]furan-7-ylcarboxamido)-(2S)-...) Show SMILES O=C(N[C@@H]1CN2CCC1CC2)c1cccc2CCOc12 |wU:3.2,(7,-4.89,;8.29,-5.71,;9.67,-4.99,;9.7,-3.44,;11.08,-2.74,;11.15,-1.2,;9.86,-.37,;8.49,-1.1,;8.42,-2.64,;9.22,-1.45,;9.86,-2.1,;8.23,-7.25,;6.86,-7.96,;6.82,-9.51,;8.12,-10.31,;9.47,-9.6,;10.91,-10.15,;11.87,-8.93,;11.02,-7.64,;9.54,-8.07,)| Show InChI InChI=1S/C16H20N2O2/c19-16(13-3-1-2-12-6-9-20-15(12)13)17-14-10-18-7-4-11(14)5-8-18/h1-3,11,14H,4-10H2,(H,17,19)/t14-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.				Bioorg Med Chem Lett 6: 263-266 (1996) Article DOI: 10.1016/0960-894X(96)00002-9 BindingDB Entry DOI: 10.7270/Q2MC90JK
					More data for this Ligand-Target Pair