BDBM50288698 CHEMBL112724::{[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-acetylamino]-methyl}-[(S)-2-((S)-3-methyl-1-phenylcarbamoyl-butylcarbamoyl)-4-phenyl-butyl]-phosphinic acid

SMILES: CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)CP(O)(=O)CNC(=O)CN1C(=O)c2ccccc2C1=O)C(=O)Nc1ccccc1

InChI Key: InChIKey=GBAPWUJOZAJNDZ-IRPSRAIASA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50288698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-1 (Homo sapiens (Human))	BDBM50288698 (CHEMBL112724 | {[2-(1,3-Dioxo-1,3-dihydro-isoindol...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)CP(O)(=O)CNC(=O)CN1C(=O)c2ccccc2C1=O)C(=O)Nc1ccccc1 Show InChI InChI=1S/C34H39N4O7P/c1-23(2)19-29(32(41)36-26-13-7-4-8-14-26)37-31(40)25(18-17-24-11-5-3-6-12-24)21-46(44,45)22-35-30(39)20-38-33(42)27-15-9-10-16-28(27)34(38)43/h3-16,23,25,29H,17-22H2,1-2H3,(H,35,39)(H,36,41)(H,37,40)(H,44,45)/t25-,29+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of stromelysin-1 (MMP-3).				Bioorg Med Chem Lett 6: 323-328 (1996) Article DOI: 10.1016/0960-894X(96)00023-6 BindingDB Entry DOI: 10.7270/Q2X0671M
					More data for this Ligand-Target Pair