BDBM50289106 2-[(E)-Hydroxyimino]-1a,2-dihydro-1H-7-oxa-cyclopropa[b]naphthalene-7a-carboxylic acid methyl-phenyl-amide::CHEMBL165828

SMILES: CN(C(=O)C12CC1C(N=O)c1ccccc1O2)c1ccccc1

InChI Key: InChIKey=RXSKYPGMYVADMC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50289106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50289106 (2-[(E)-Hydroxyimino]-1a,2-dihydro-1H-7-oxa-cyclopr...) Show SMILES CN(C(=O)C12CC1C(N=O)c1ccccc1O2)c1ccccc1 Show InChI InChI=1S/C18H16N2O3/c1-20(12-7-3-2-4-8-12)17(21)18-11-14(18)16(19-22)13-9-5-6-10-15(13)23-18/h2-10,14,16H,11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.				Bioorg Med Chem Lett 6: 763-766 (1996) Article DOI: 10.1016/0960-894X(96)00104-7 BindingDB Entry DOI: 10.7270/Q2WS8T7Q
					More data for this Ligand-Target Pair