BDBM50289300 6-(4-Methylsulfanyl-phenyl)-5-phenyl-imidazo[2,1-b]thiazole::CHEMBL148666

SMILES: CSc1ccc(cc1)-c1nc2sccn2c1-c1ccccc1

InChI Key: InChIKey=LGGOJTFFASIAEW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289300   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50289300 (6-(4-Methylsulfanyl-phenyl)-5-phenyl-imidazo[2,1-b...) Show SMILES CSc1ccc(cc1)-c1nc2sccn2c1-c1ccccc1 Show InChI InChI=1S/C18H14N2S2/c1-21-15-9-7-13(8-10-15)16-17(14-5-3-2-4-6-14)20-11-12-22-18(20)19-16/h2-12H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of the production of PGE-2 in arachidonic acid stimulated chinese hamster ovary (CHO) cellstransfected with human cyclooxygenase-...				Bioorg Med Chem Lett 7: 47-52 (1997) Article DOI: 10.1016/S0960-894X(96)00580-X BindingDB Entry DOI: 10.7270/Q2FN166R
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50289300 (6-(4-Methylsulfanyl-phenyl)-5-phenyl-imidazo[2,1-b...) Show SMILES CSc1ccc(cc1)-c1nc2sccn2c1-c1ccccc1 Show InChI InChI=1S/C18H14N2S2/c1-21-15-9-7-13(8-10-15)16-17(14-5-3-2-4-6-14)20-11-12-22-18(20)19-16/h2-12H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of the production of PGE-2 in arachidonic acid stimulated chinese hamster ovary (CHO) cellstransfected with human cyclooxygenase-...				Bioorg Med Chem Lett 7: 47-52 (1997) Article DOI: 10.1016/S0960-894X(96)00580-X BindingDB Entry DOI: 10.7270/Q2FN166R
					More data for this Ligand-Target Pair