null

SMILES: Cc1cccc(c1)-c1c(sc2nc(nn12)C(F)(F)F)-c1ccc(cc1)S(C)(=O)=O

InChI Key: InChIKey=LZOIEGWIVVWHNS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50289327 (5-(4-Methanesulfonyl-phenyl)-6-m-tolyl-2-trifluoro...) Show SMILES Cc1cccc(c1)-c1c(sc2nc(nn12)C(F)(F)F)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H14F3N3O2S2/c1-11-4-3-5-13(10-11)15-16(12-6-8-14(9-7-12)29(2,26)27)28-18-23-17(19(20,21)22)24-25(15)18/h3-10H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cells				Bioorg Med Chem Lett 7: 57-62 (1997) Article DOI: 10.1016/S0960-894X(96)00582-3 BindingDB Entry DOI: 10.7270/Q29W0FG1
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50289327 (5-(4-Methanesulfonyl-phenyl)-6-m-tolyl-2-trifluoro...) Show SMILES Cc1cccc(c1)-c1c(sc2nc(nn12)C(F)(F)F)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H14F3N3O2S2/c1-11-4-3-5-13(10-11)15-16(12-6-8-14(9-7-12)29(2,26)27)28-18-23-17(19(20,21)22)24-25(15)18/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.02E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of COX2 (unknown origin) expressed in CHO cells				Citation and Details Article DOI: 10.1007/s00044-004-0039-1 BindingDB Entry DOI: 10.7270/Q2280BHV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50289327 (5-(4-Methanesulfonyl-phenyl)-6-m-tolyl-2-trifluoro...) Show SMILES Cc1cccc(c1)-c1c(sc2nc(nn12)C(F)(F)F)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H14F3N3O2S2/c1-11-4-3-5-13(10-11)15-16(12-6-8-14(9-7-12)29(2,26)27)28-18-23-17(19(20,21)22)24-25(15)18/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 2 in chinese hamster ovary (CHO) cells				Bioorg Med Chem Lett 7: 57-62 (1997) Article DOI: 10.1016/S0960-894X(96)00582-3 BindingDB Entry DOI: 10.7270/Q29W0FG1
					More data for this Ligand-Target Pair