BDBM50289609 4-Furan-3-yl-2-(4-methyl-piperazin-1-yl)-6-phenyl-pyrimidine::CHEMBL43434

SMILES: CN1CCN(CC1)c1nc(cc(n1)-c1ccccc1)-c1ccoc1

InChI Key: InChIKey=UQWHVDPVOKMRDD-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289609   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50289609 (4-Furan-3-yl-2-(4-methyl-piperazin-1-yl)-6-phenyl-...) Show SMILES CN1CCN(CC1)c1nc(cc(n1)-c1ccccc1)-c1ccoc1 Show InChI InChI=1S/C19H20N4O/c1-22-8-10-23(11-9-22)19-20-17(15-5-3-2-4-6-15)13-18(21-19)16-7-12-24-14-16/h2-7,12-14H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from 5-hydroxytryptamine 2A receptor of rat brain cortex				Bioorg Med Chem Lett 7: 1635-1638 (1997) Article DOI: 10.1016/S0960-894X(97)00291-6 BindingDB Entry DOI: 10.7270/Q2QZ29ZT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50289609 (4-Furan-3-yl-2-(4-methyl-piperazin-1-yl)-6-phenyl-...) Show SMILES CN1CCN(CC1)c1nc(cc(n1)-c1ccccc1)-c1ccoc1 Show InChI InChI=1S/C19H20N4O/c1-22-8-10-23(11-9-22)19-20-17(15-5-3-2-4-6-15)13-18(21-19)16-7-12-24-14-16/h2-7,12-14H,8-11H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat brain hippocampus				Bioorg Med Chem Lett 7: 1635-1638 (1997) Article DOI: 10.1016/S0960-894X(97)00291-6 BindingDB Entry DOI: 10.7270/Q2QZ29ZT
					More data for this Ligand-Target Pair