BDBM50290038 CHEMBL419441::Potassium; (5R,6S)-3-tert-butyl-6-((R)-1-hydroxy-ethyl)-4,7-dioxo-4lambda*4*-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylate

SMILES: C[C@@H](O)[C@@H]1[C@@H]2N(C1=O)C(C([O-])=O)=C(S2=O)C(C)(C)C

InChI Key: InChIKey=GSVZWBPOOFMGAJ-PISQCCPLSA-M

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-lactamase (TEM-1) (Escherichia coli)	BDBM50290038 (CHEMBL419441 | Potassium; (5R,6S)-3-tert-butyl-6-(...) Show SMILES C[C@@H](O)[C@@H]1[C@@H]2N(C1=O)C(C([O-])=O)=C(S2=O)C(C)(C)C |c:12| Show InChI InChI=1S/C12H17NO5S/c1-5(14)6-9(15)13-7(11(16)17)8(12(2,3)4)19(18)10(6)13/h5-6,10,14H,1-4H3,(H,16,17)/p-1/t5-,6+,10-,19?/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for beta-lactamase inhibition activity of Escherichia coli after 15 min of preincubation with the enzyme at 37 degree C				Bioorg Med Chem Lett 7: 2217-2222 (1997) Article DOI: 10.1016/S0960-894X(97)00401-0 BindingDB Entry DOI: 10.7270/Q2M32VR6
					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50290038 (CHEMBL419441 | Potassium; (5R,6S)-3-tert-butyl-6-(...) Show SMILES C[C@@H](O)[C@@H]1[C@@H]2N(C1=O)C(C([O-])=O)=C(S2=O)C(C)(C)C |c:12| Show InChI InChI=1S/C12H17NO5S/c1-5(14)6-9(15)13-7(11(16)17)8(12(2,3)4)19(18)10(6)13/h5-6,10,14H,1-4H3,(H,16,17)/p-1/t5-,6+,10-,19?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for beta-lactamase inhibition activity of Enterobacter cloacae after 15 min of preincubation with the enzyme at 37 degree C				Bioorg Med Chem Lett 7: 2217-2222 (1997) Article DOI: 10.1016/S0960-894X(97)00401-0 BindingDB Entry DOI: 10.7270/Q2M32VR6
					More data for this Ligand-Target Pair