BDBM50290560 2-[[6-(Biphenyl-4-ylamino)-9-isopropyl-9H-purin-2-yl]-(2-hydroxy-ethyl)-amino]-ethanol::CHEMBL93892

SMILES: CC(C)n1cnc2c(Nc3ccc(cc3)-c3ccccc3)nc(nc12)N(CCO)CCO

InChI Key: InChIKey=GHVQYGTVRHBCLP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290560   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK2/Cyclin E/G1/S-specific cyclin E2 (Homo sapiens (Human))	BDBM50290560 (2-[[6-(Biphenyl-4-ylamino)-9-isopropyl-9H-purin-2-...) Show SMILES CC(C)n1cnc2c(Nc3ccc(cc3)-c3ccccc3)nc(nc12)N(CCO)CCO Show InChI InChI=1S/C24H28N6O2/c1-17(2)30-16-25-21-22(27-24(28-23(21)30)29(12-14-31)13-15-32)26-20-10-8-19(9-11-20)18-6-4-3-5-7-18/h3-11,16-17,31-32H,12-15H2,1-2H3,(H,26,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin E				Bioorg Med Chem Lett 7: 2697-2702 (1997) Article DOI: 10.1016/S0960-894X(97)10076-2 BindingDB Entry DOI: 10.7270/Q2FJ2H8Q
					More data for this Ligand-Target Pair