BDBM50290563 2-[[6-(4-Bromo-benzylamino)-9-isopropyl-9H-purin-2-yl]-(2-hydroxy-ethyl)-amino]-ethanol::CHEMBL92544

SMILES: CC(C)n1cnc2c(NCc3ccc(Br)cc3)nc(nc12)N(CCO)CCO

InChI Key: InChIKey=KXWPJLNSYQKTCM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290563   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK2/Cyclin E/G1/S-specific cyclin E2 (Homo sapiens (Human))	BDBM50290563 (2-[[6-(4-Bromo-benzylamino)-9-isopropyl-9H-purin-2...) Show SMILES CC(C)n1cnc2c(NCc3ccc(Br)cc3)nc(nc12)N(CCO)CCO Show InChI InChI=1S/C19H25BrN6O2/c1-13(2)26-12-22-16-17(21-11-14-3-5-15(20)6-4-14)23-19(24-18(16)26)25(7-9-27)8-10-28/h3-6,12-13,27-28H,7-11H2,1-2H3,(H,21,23,24)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin E				Bioorg Med Chem Lett 7: 2697-2702 (1997) Article DOI: 10.1016/S0960-894X(97)10076-2 BindingDB Entry DOI: 10.7270/Q2FJ2H8Q
					More data for this Ligand-Target Pair