BDBM50290567 2-[[6-(Cyclopropyl-methyl-amino)-9-isopropyl-9H-purin-2-yl]-(2-hydroxy-ethyl)-amino]-ethanol::CHEMBL316276

SMILES: CC(C)n1cnc2c(nc(nc12)N(CCO)CCO)N(C)C1CC1

InChI Key: InChIKey=HELDPPIFNGOVFE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK2/Cyclin E/G1/S-specific cyclin E2 (Homo sapiens (Human))	BDBM50290567 (2-[[6-(Cyclopropyl-methyl-amino)-9-isopropyl-9H-pu...) Show SMILES CC(C)n1cnc2c(nc(nc12)N(CCO)CCO)N(C)C1CC1 Show InChI InChI=1S/C16H26N6O2/c1-11(2)22-10-17-13-14(20(3)12-4-5-12)18-16(19-15(13)22)21(6-8-23)7-9-24/h10-12,23-24H,4-9H2,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin E				Bioorg Med Chem Lett 7: 2697-2702 (1997) Article DOI: 10.1016/S0960-894X(97)10076-2 BindingDB Entry DOI: 10.7270/Q2FJ2H8Q
					More data for this Ligand-Target Pair