BDBM50290572 (2-Chloro-9-methyl-9H-purin-6-yl)-(2-methoxy-ethyl)-amine::CHEMBL91116

SMILES: COCCNc1nc(Cl)nc2n(C)cnc12

InChI Key: InChIKey=SJIFGRLVYKMMIG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290572   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDK2/Cyclin E/G1/S-specific cyclin E2 (Homo sapiens (Human))	BDBM50290572 ((2-Chloro-9-methyl-9H-purin-6-yl)-(2-methoxy-ethyl...) Show SMILES COCCNc1nc(Cl)nc2n(C)cnc12 Show InChI InChI=1S/C9H12ClN5O/c1-15-5-12-6-7(11-3-4-16-2)13-9(10)14-8(6)15/h5H,3-4H2,1-2H3,(H,11,13,14)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin E				Bioorg Med Chem Lett 7: 2697-2702 (1997) Article DOI: 10.1016/S0960-894X(97)10076-2 BindingDB Entry DOI: 10.7270/Q2FJ2H8Q
					More data for this Ligand-Target Pair