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SMILES: COc1ccc(CNc2nc(nc3n(CC(C)C)cnc23)N(CCO)CCO)cc1

InChI Key: InChIKey=ISJZNCJWKJNECF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290603   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2


(Homo sapiens (Human))		BDBM50290603
PNG
(2-{(2-Hydroxy-ethyl)-[9-isobutyl-6-(4-methoxy-benz...)
Show SMILES COc1ccc(CNc2nc(nc3n(CC(C)C)cnc23)N(CCO)CCO)cc1
Show InChI InChI=1S/C21H30N6O3/c1-15(2)13-27-14-23-18-19(22-12-16-4-6-17(30-3)7-5-16)24-21(25-20(18)27)26(8-10-28)9-11-29/h4-7,14-15,28-29H,8-13H2,1-3H3,(H,22,24,25)
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PC cid
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Similars
Article
n/an/a 2.00E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin E

Bioorg Med Chem Lett 7: 2697-2702 (1997)


Article DOI: 10.1016/S0960-894X(97)10076-2
BindingDB Entry DOI: 10.7270/Q2FJ2H8Q
More data for this
Ligand-Target Pair