BDBM50290617 2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(quinolin-8-ylamino)-9H-purin-2-yl]-amino}-ethanol::CHEMBL329440

SMILES: CC(C)n1cnc2c(Nc3cccc4cccnc34)nc(nc12)N(CCO)CCO

InChI Key: InChIKey=VJLZOULTWGPOQQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290617   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2 (Homo sapiens (Human))	BDBM50290617 (2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(quinolin-8-yl...) Show SMILES CC(C)n1cnc2c(Nc3cccc4cccnc34)nc(nc12)N(CCO)CCO Show InChI InChI=1S/C21H25N7O2/c1-14(2)28-13-23-18-19(24-16-7-3-5-15-6-4-8-22-17(15)16)25-21(26-20(18)28)27(9-11-29)10-12-30/h3-8,13-14,29-30H,9-12H2,1-2H3,(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin E				Bioorg Med Chem Lett 7: 2697-2702 (1997) Article DOI: 10.1016/S0960-894X(97)10076-2 BindingDB Entry DOI: 10.7270/Q2FJ2H8Q
					More data for this Ligand-Target Pair