BDBM50290842 6,7-Dimethoxy-4-(4-methoxy-phenoxy)-quinoline::CHEMBL98584
SMILES: COc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cc1
InChI Key: InChIKey=GBYWCVLXEHHOFE-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet-derived growth factor receptor (PDGFr) (Rattus norvegicus) | BDBM50290842 (6,7-Dimethoxy-4-(4-methoxy-phenoxy)-quinoline | CH...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of PDGF-BB induced PDGF-B receptor autophosphorylation in rat mesangial cells. | Bioorg Med Chem Lett 7: 2935-2940 (1997) Article DOI: 10.1016/S0960-894X(97)10117-2 BindingDB Entry DOI: 10.7270/Q20Z738R | |||||||||||
More data for this Ligand-Target Pair |