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SMILES: CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)C1C(=C1c1cccc(Cl)c1)c1ccccc1

InChI Key: InChIKey=YLSWYZBILYWGQN-XAWUTYGVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290978   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Homo sapiens (Human))		BDBM50290978
PNG
(2-(3-Chloro-phenyl)-3-phenyl-cycloprop-2-enecarbox...)
Show SMILES CN([C@H]1CCCC[C@@H]1N1CCCC1)C(=O)C1C(=C1c1cccc(Cl)c1)c1ccccc1 |c:18|
Show InChI InChI=1S/C27H31ClN2O/c1-29(22-14-5-6-15-23(22)30-16-7-8-17-30)27(31)26-24(19-10-3-2-4-11-19)25(26)20-12-9-13-21(28)18-20/h2-4,9-13,18,22-23,26H,5-8,14-17H2,1H3/t22-,23-,26?/m0/s1
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Similars
Article
n/an/an/an/a 141n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Opioid receptor kappa 1 as reduced contraction in electrically stimulated rabbit vas deferens

Bioorg Med Chem Lett 7: 291-296 (1997)


Article DOI: 10.1016/S0960-894X(96)00615-4
BindingDB Entry DOI: 10.7270/Q2G160VS
More data for this
Ligand-Target Pair