BDBM50291461 CHEMBL173394::N-Methyl-N'-[6-(3-phenyl-propoxy)-biphenyl-3-yl]-guanidine

SMILES: CNC(N)=Nc1ccc(OCCCc2ccccc2)c(c1)-c1ccccc1

InChI Key: InChIKey=IIIZADYKFQXOMP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50291461   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human))	BDBM50291461 (CHEMBL173394 | N-Methyl-N'-[6-(3-phenyl-propoxy)-b...) Show SMILES CNC(N)=Nc1ccc(OCCCc2ccccc2)c(c1)-c1ccccc1 |w:4.4| Show InChI InChI=1S/C23H25N3O/c1-25-23(24)26-20-14-15-22(21(17-20)19-12-6-3-7-13-19)27-16-8-11-18-9-4-2-5-10-18/h2-7,9-10,12-15,17H,8,11,16H2,1H3,(H3,24,25,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against C5a anaphylatoxin chemotactic receptor assayed on human monocyte cell line U937				Bioorg Med Chem Lett 7: 907-912 (1997) Article DOI: 10.1016/S0960-894X(97)00124-8 BindingDB Entry DOI: 10.7270/Q2JM29MB
					More data for this Ligand-Target Pair