BDBM50291470 CHEMBL425497::N-(4-Benzyloxy-3-naphthalen-1-yl-phenyl)-N'-methyl-guanidine

SMILES: CNC(N)=Nc1ccc(OCc2ccccc2)c(c1)-c1cccc2ccccc12

InChI Key: InChIKey=ROGVXXTUQXSUAI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50291470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human))	BDBM50291470 (CHEMBL425497 | N-(4-Benzyloxy-3-naphthalen-1-yl-ph...) Show SMILES CNC(N)=Nc1ccc(OCc2ccccc2)c(c1)-c1cccc2ccccc12 |w:4.4| Show InChI InChI=1S/C25H23N3O/c1-27-25(26)28-20-14-15-24(29-17-18-8-3-2-4-9-18)23(16-20)22-13-7-11-19-10-5-6-12-21(19)22/h2-16H,17H2,1H3,(H3,26,27,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against C5a anaphylatoxin chemotactic receptor assayed on human monocyte cell line U937				Bioorg Med Chem Lett 7: 907-912 (1997) Article DOI: 10.1016/S0960-894X(97)00124-8 BindingDB Entry DOI: 10.7270/Q2JM29MB
					More data for this Ligand-Target Pair