BDBM50291486 2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-ethyl]-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL368780

SMILES: Cc1noc(NS(=O)(=O)c2ccsc2CCc2cc3OCOc3cc2C)c1Br

InChI Key: InChIKey=LBPJEBLOIGXYMG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291486   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50291486 (2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-ethyl]-thiop...) Show SMILES Cc1noc(NS(=O)(=O)c2ccsc2CCc2cc3OCOc3cc2C)c1Br Show InChI InChI=1S/C18H17BrN2O5S2/c1-10-7-13-14(25-9-24-13)8-12(10)3-4-15-16(5-6-27-15)28(22,23)21-18-17(19)11(2)20-26-18/h5-8,21H,3-4,9H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assay				Bioorg Med Chem Lett 7: 939-944 (1997) Article DOI: 10.1016/S0960-894X(97)00133-9 BindingDB Entry DOI: 10.7270/Q2959HKC
					More data for this Ligand-Target Pair
EDNRB (Homo sapiens (Human))	BDBM50291486 (2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-ethyl]-thiop...) Show SMILES Cc1noc(NS(=O)(=O)c2ccsc2CCc2cc3OCOc3cc2C)c1Br Show InChI InChI=1S/C18H17BrN2O5S2/c1-10-7-13-14(25-9-24-13)8-12(10)3-4-15-16(5-6-27-15)28(22,23)21-18-17(19)11(2)20-26-18/h5-8,21H,3-4,9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assay				Bioorg Med Chem Lett 7: 939-944 (1997) Article DOI: 10.1016/S0960-894X(97)00133-9 BindingDB Entry DOI: 10.7270/Q2959HKC
					More data for this Ligand-Target Pair