BDBM50291487 3-(2-Benzo[1,3]dioxol-5-yl-ethyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL177070

SMILES: Cc1noc(NS(=O)(=O)c2sccc2CCc2ccc3OCOc3c2)c1Br

InChI Key: InChIKey=WIUBNUWPUWBVSS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291487   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EDNRB (Homo sapiens (Human))	BDBM50291487 (3-(2-Benzo[1,3]dioxol-5-yl-ethyl)-thiophene-2-sulf...) Show SMILES Cc1noc(NS(=O)(=O)c2sccc2CCc2ccc3OCOc3c2)c1Br Show InChI InChI=1S/C17H15BrN2O5S2/c1-10-15(18)16(25-19-10)20-27(21,22)17-12(6-7-26-17)4-2-11-3-5-13-14(8-11)24-9-23-13/h3,5-8,20H,2,4,9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assay				Bioorg Med Chem Lett 7: 939-944 (1997) Article DOI: 10.1016/S0960-894X(97)00133-9 BindingDB Entry DOI: 10.7270/Q2959HKC
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50291487 (3-(2-Benzo[1,3]dioxol-5-yl-ethyl)-thiophene-2-sulf...) Show SMILES Cc1noc(NS(=O)(=O)c2sccc2CCc2ccc3OCOc3c2)c1Br Show InChI InChI=1S/C17H15BrN2O5S2/c1-10-15(18)16(25-19-10)20-27(21,22)17-12(6-7-26-17)4-2-11-3-5-13-14(8-11)24-9-23-13/h3,5-8,20H,2,4,9H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	237	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assay				Bioorg Med Chem Lett 7: 939-944 (1997) Article DOI: 10.1016/S0960-894X(97)00133-9 BindingDB Entry DOI: 10.7270/Q2959HKC
					More data for this Ligand-Target Pair