BDBM50291494 3-(2-p-Tolyl-ethyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL366364

SMILES: Cc1noc(NS(=O)(=O)c2sccc2CCc2ccc(C)cc2)c1Br

InChI Key: InChIKey=JRGZXJBKZBEYCZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291494   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EDNRB (Homo sapiens (Human))	BDBM50291494 (3-(2-p-Tolyl-ethyl)-thiophene-2-sulfonic acid (4-b...) Show SMILES Cc1noc(NS(=O)(=O)c2sccc2CCc2ccc(C)cc2)c1Br Show InChI InChI=1S/C17H17BrN2O3S2/c1-11-3-5-13(6-4-11)7-8-14-9-10-24-17(14)25(21,22)20-16-15(18)12(2)19-23-16/h3-6,9-10,20H,7-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	9.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human Endothelin B receptor using I-ET-1 as radioligand in a competitive radioligand assay				Bioorg Med Chem Lett 7: 939-944 (1997) Article DOI: 10.1016/S0960-894X(97)00133-9 BindingDB Entry DOI: 10.7270/Q2959HKC
					More data for this Ligand-Target Pair
Endothelin-1 receptor (Homo sapiens (Human))	BDBM50291494 (3-(2-p-Tolyl-ethyl)-thiophene-2-sulfonic acid (4-b...) Show SMILES Cc1noc(NS(=O)(=O)c2sccc2CCc2ccc(C)cc2)c1Br Show InChI InChI=1S/C17H17BrN2O3S2/c1-11-3-5-13(6-4-11)7-8-14-9-10-24-17(14)25(21,22)20-16-15(18)12(2)19-23-16/h3-6,9-10,20H,7-8H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	347	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory of human Endothelin A receptor by using I-ET-1 as radioligand in a competitive radioligand assay				Bioorg Med Chem Lett 7: 939-944 (1997) Article DOI: 10.1016/S0960-894X(97)00133-9 BindingDB Entry DOI: 10.7270/Q2959HKC
					More data for this Ligand-Target Pair