BDBM50291553 CHEMBL10436::{1-[(R)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethylamino]-2-quinolin-8-yl-ethyl}-phosphonic acid

SMILES: OP(O)(=O)C(Cc1cccc2cccnc12)N[C@H](Cc1ccc(cc1)-c1ccccc1)c1nnn[nH]1

InChI Key: InChIKey=RZMPSTCSWYMNIQ-MIHMCVIASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50291553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50291553 (CHEMBL10436 | {1-[(R)-2-Biphenyl-4-yl-1-(1H-tetraz...) Show SMILES OP(O)(=O)C(Cc1cccc2cccnc12)N[C@H](Cc1ccc(cc1)-c1ccccc1)c1nnn[nH]1 Show InChI InChI=1S/C26H25N6O3P/c33-36(34,35)24(17-22-9-4-8-21-10-5-15-27-25(21)22)28-23(26-29-31-32-30-26)16-18-11-13-20(14-12-18)19-6-2-1-3-7-19/h1-15,23-24,28H,16-17H2,(H2,33,34,35)(H,29,30,31,32)/t23-,24?/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition against recombinant human Endothelin converting enzyme 1 activity				Bioorg Med Chem Lett 7: 1059-1064 (1997) Article DOI: 10.1016/S0960-894X(97)00159-5 BindingDB Entry DOI: 10.7270/Q2WH2QGK
					More data for this Ligand-Target Pair