BDBM50291554 CHEMBL10055::{2-Benzo[1,3]dioxol-4-yl-1-[(R)-2-biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethylamino]-ethyl}-phosphonic acid

SMILES: OP(O)(=O)C(Cc1cccc2OCOc12)N[C@H](Cc1ccc(cc1)-c1ccccc1)c1nnn[nH]1

InChI Key: InChIKey=XVTHDQIYTRAPLI-PSDZMVHGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50291554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-converting enzyme 1 (ECE1) (Homo sapiens (Human))	BDBM50291554 (CHEMBL10055 | {2-Benzo[1,3]dioxol-4-yl-1-[(R)-2-bi...) Show SMILES OP(O)(=O)C(Cc1cccc2OCOc12)N[C@H](Cc1ccc(cc1)-c1ccccc1)c1nnn[nH]1 Show InChI InChI=1S/C24H24N5O5P/c30-35(31,32)22(14-19-7-4-8-21-23(19)34-15-33-21)25-20(24-26-28-29-27-24)13-16-9-11-18(12-10-16)17-5-2-1-3-6-17/h1-12,20,22,25H,13-15H2,(H2,30,31,32)(H,26,27,28,29)/t20-,22?/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition against recombinant human Endothelin converting enzyme 1 activity				Bioorg Med Chem Lett 7: 1059-1064 (1997) Article DOI: 10.1016/S0960-894X(97)00159-5 BindingDB Entry DOI: 10.7270/Q2WH2QGK
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