BDBM50291753 2-Ethylamino-5-methyl-benzo[d][1,3]oxazin-4-one::CHEMBL142781

SMILES: CCNc1nc2cccc(C)c2c(=O)o1

InChI Key: InChIKey=KDRJPSFCCXLIFK-UHFFFAOYSA-N

Data: 2 KI  2 K_off  1 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50291753   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50291753 (2-Ethylamino-5-methyl-benzo[d][1,3]oxazin-4-one | ...) Show SMILES CCNc1nc2cccc(C)c2c(=O)o1 Show InChI InChI=1S/C11H12N2O2/c1-3-12-11-13-8-6-4-5-7(2)9(8)10(14)15-11/h4-6H,3H2,1-2H3,(H,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	31.6	n/a	n/a	n/a	n/a	0.00178	5.25E+4	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Component deacylation rate constant for interaction with human leukocyte elastase				J Med Chem 33: 464-79 (1990) Checked by Author BindingDB Entry DOI: 10.7270/Q2PR7X6X
					More data for this Ligand-Target Pair
Leukocyte elastase (Homo sapiens (Human))	BDBM50291753 (2-Ethylamino-5-methyl-benzo[d][1,3]oxazin-4-one | ...) Show SMILES CCNc1nc2cccc(C)c2c(=O)o1 Show InChI InChI=1S/C11H12N2O2/c1-3-12-11-13-8-6-4-5-7(2)9(8)10(14)15-11/h4-6H,3H2,1-2H3,(H,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Rate of deacylation by human leukocyte elastase				J Med Chem 30: 589-591 (1987) Article DOI: 10.1021/jm00387a001 BindingDB Entry DOI: 10.7270/Q2GQ6XRH
					More data for this Ligand-Target Pair
Leukocyte elastase (Homo sapiens (Human))	BDBM50291753 (2-Ethylamino-5-methyl-benzo[d][1,3]oxazin-4-one | ...) Show SMILES CCNc1nc2cccc(C)c2c(=O)o1 Show InChI InChI=1S/C11H12N2O2/c1-3-12-11-13-8-6-4-5-7(2)9(8)10(14)15-11/h4-6H,3H2,1-2H3,(H,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	0.00180	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Rate of deacylation by human leukocyte elastase				J Med Chem 30: 589-591 (1987) Article DOI: 10.1021/jm00387a001 BindingDB Entry DOI: 10.7270/Q2GQ6XRH
					More data for this Ligand-Target Pair