BDBM50291928 (4S,7S)-2-Benzoyl-7-chloro-3-methyl-4-(1-methyl-1H-tetrazol-5-ylsulfanyl)-5,5-dioxo-5lambda*6*-thia-1-aza-bicyclo[4.2.0]oct-2-en-8-one::CHEMBL334343

SMILES: CC1=C(N2C([C@@H](Cl)C2=O)S(=O)(=O)[C@@H]1Sc1nnnn1C)C(=O)c1ccccc1

InChI Key: InChIKey=UWWDCBAYMIOXQW-WAJWKUKPSA-N

Data: 1 K_on

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50291928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50291928 ((4S,7S)-2-Benzoyl-7-chloro-3-methyl-4-(1-methyl-1H...) Show SMILES CC1=C(N2C([C@@H](Cl)C2=O)S(=O)(=O)[C@@H]1Sc1nnnn1C)C(=O)c1ccccc1 |t:1| Show InChI InChI=1S/C16H14ClN5O4S2/c1-8-11(12(23)9-6-4-3-5-7-9)22-13(24)10(17)14(22)28(25,26)15(8)27-16-18-19-20-21(16)2/h3-7,10,14-15H,1-2H3/t10-,14?,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	n/a	n/a	1.30	n/a	n/a
Pharmacia Farmitalia Carlo Erba Curated by ChEMBL					Assay Description Tested for the rate constant against Human Leukocyte Elastase (HLE) inactivation				J Med Chem 37: 4003-19 (1994) BindingDB Entry DOI: 10.7270/Q2T43S5B
					More data for this Ligand-Target Pair