BDBM50291975 CHEMBL4167914

SMILES: Cc1cc(cc(C)c1Nc1ccnc(Nc2ccc(cc2)C#N)n1)-c1ccccc1Cl

InChI Key: InChIKey=MYZDQYGTUAEWLQ-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50291975   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50291975 (CHEMBL4167914) Show SMILES Cc1cc(cc(C)c1Nc1ccnc(Nc2ccc(cc2)C#N)n1)-c1ccccc1Cl Show InChI InChI=1S/C25H20ClN5/c1-16-13-19(21-5-3-4-6-22(21)26)14-17(2)24(16)30-23-11-12-28-25(31-23)29-20-9-7-18(15-27)8-10-20/h3-14H,1-2H3,(H2,28,29,30,31)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant wild type HIV1 reverse transcriptase p66/p51 using poly (rA)/anoligo (dT)16 as template/primer assessed as inhibition of bi...				Eur J Med Chem 145: 726-734 (2018) Article DOI: 10.1016/j.ejmech.2018.01.016 BindingDB Entry DOI: 10.7270/Q21C20DV
					More data for this Ligand-Target Pair