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SMILES: Cc1cc(cc(C)c1Nc1ccnc(Nc2ccc(cc2)C#N)n1)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=PPBACBMUIDHVDG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292181   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50292181
PNG
(CHEMBL4172683)
Show SMILES Cc1cc(cc(C)c1Nc1ccnc(Nc2ccc(cc2)C#N)n1)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C26H20F3N5/c1-16-13-20(19-5-7-21(8-6-19)26(27,28)29)14-17(2)24(16)33-23-11-12-31-25(34-23)32-22-9-3-18(15-30)4-10-22/h3-14H,1-2H3,(H2,31,32,33,34)
PDB
MMDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 67n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant wild type HIV1 reverse transcriptase p66/p51 using poly (rA)/anoligo (dT)16 as template/primer assessed as inhibition of bi...

Eur J Med Chem 145: 726-734 (2018)


Article DOI: 10.1016/j.ejmech.2018.01.016
BindingDB Entry DOI: 10.7270/Q21C20DV
More data for this
Ligand-Target Pair