BDBM50292206 CHEMBL4161215

SMILES: Cc1cc(cc(C)c1Nc1ccnc(Nc2ccc(cc2)C#N)n1)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=CTQRTSFDXNIPBR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50292206 (CHEMBL4161215) Show SMILES Cc1cc(cc(C)c1Nc1ccnc(Nc2ccc(cc2)C#N)n1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C26H20F3N5/c1-16-12-20(19-4-3-5-21(14-19)26(27,28)29)13-17(2)24(16)33-23-10-11-31-25(34-23)32-22-8-6-18(15-30)7-9-22/h3-14H,1-2H3,(H2,31,32,33,34)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant wild type HIV1 reverse transcriptase p66/p51 using poly (rA)/anoligo (dT)16 as template/primer assessed as inhibition of bi...				Eur J Med Chem 145: 726-734 (2018) Article DOI: 10.1016/j.ejmech.2018.01.016 BindingDB Entry DOI: 10.7270/Q21C20DV
					More data for this Ligand-Target Pair