Found 5 hits for monomerid = 50292294 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity protein phosphatase (VHR)
(Homo sapiens (Human)) | BDBM50292294
(4-(5-((3-carboxy-4-hydroxyphenyl)amino)-5-oxopenta...)Show SMILES CC1(C)CC(CC(C)(C)N1[O])NC(=O)CCCC(=O)Nc1ccc(O)c(c1)C(O)=O |^1:10| Show InChI InChI=1S/C21H30N3O6/c1-20(2)11-14(12-21(3,4)24(20)30)23-18(27)7-5-6-17(26)22-13-8-9-16(25)15(10-13)19(28)29/h8-10,14,25H,5-7,11-12H2,1-4H3,(H,22,26)(H,23,27)(H,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Medical Research
Curated by ChEMBL
| Assay Description Inhibition of VHR |
J Med Chem 50: 2137-43 (2007)
Article DOI: 10.1021/jm061481l BindingDB Entry DOI: 10.7270/Q2BG2NP4 |
More data for this Ligand-Target Pair | |
Hematopoietic protein-tyrosine phosphatase (HEPTP)
(Homo sapiens (Human)) | BDBM50292294
(4-(5-((3-carboxy-4-hydroxyphenyl)amino)-5-oxopenta...)Show SMILES CC1(C)CC(CC(C)(C)N1[O])NC(=O)CCCC(=O)Nc1ccc(O)c(c1)C(O)=O |^1:10| Show InChI InChI=1S/C21H30N3O6/c1-20(2)11-14(12-21(3,4)24(20)30)23-18(27)7-5-6-17(26)22-13-8-9-16(25)15(10-13)19(28)29/h8-10,14,25H,5-7,11-12H2,1-4H3,(H,22,26)(H,23,27)(H,28,29) | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Medical Research
Curated by ChEMBL
| Assay Description Inhibition of HePTP |
J Med Chem 50: 2137-43 (2007)
Article DOI: 10.1021/jm061481l BindingDB Entry DOI: 10.7270/Q2BG2NP4 |
More data for this Ligand-Target Pair | |
Leukocyte common antigen
(Homo sapiens (Human)) | BDBM50292294
(4-(5-((3-carboxy-4-hydroxyphenyl)amino)-5-oxopenta...)Show SMILES CC1(C)CC(CC(C)(C)N1[O])NC(=O)CCCC(=O)Nc1ccc(O)c(c1)C(O)=O |^1:10| Show InChI InChI=1S/C21H30N3O6/c1-20(2)11-14(12-21(3,4)24(20)30)23-18(27)7-5-6-17(26)22-13-8-9-16(25)15(10-13)19(28)29/h8-10,14,25H,5-7,11-12H2,1-4H3,(H,22,26)(H,23,27)(H,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Medical Research
Curated by ChEMBL
| Assay Description Inhibition of CD45 |
J Med Chem 50: 2137-43 (2007)
Article DOI: 10.1021/jm061481l BindingDB Entry DOI: 10.7270/Q2BG2NP4 |
More data for this Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 2
(Homo sapiens (Human)) | BDBM50292294
(4-(5-((3-carboxy-4-hydroxyphenyl)amino)-5-oxopenta...)Show SMILES CC1(C)CC(CC(C)(C)N1[O])NC(=O)CCCC(=O)Nc1ccc(O)c(c1)C(O)=O |^1:10| Show InChI InChI=1S/C21H30N3O6/c1-20(2)11-14(12-21(3,4)24(20)30)23-18(27)7-5-6-17(26)22-13-8-9-16(25)15(10-13)19(28)29/h8-10,14,25H,5-7,11-12H2,1-4H3,(H,22,26)(H,23,27)(H,28,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Medical Research
Curated by ChEMBL
| Assay Description Inhibition of TCPTP |
J Med Chem 50: 2137-43 (2007)
Article DOI: 10.1021/jm061481l BindingDB Entry DOI: 10.7270/Q2BG2NP4 |
More data for this Ligand-Target Pair | |
Protein-tyrosine phosphatase 1B
(Homo sapiens (Human)) | BDBM50292294
(4-(5-((3-carboxy-4-hydroxyphenyl)amino)-5-oxopenta...)Show SMILES CC1(C)CC(CC(C)(C)N1[O])NC(=O)CCCC(=O)Nc1ccc(O)c(c1)C(O)=O |^1:10| Show InChI InChI=1S/C21H30N3O6/c1-20(2)11-14(12-21(3,4)24(20)30)23-18(27)7-5-6-17(26)22-13-8-9-16(25)15(10-13)19(28)29/h8-10,14,25H,5-7,11-12H2,1-4H3,(H,22,26)(H,23,27)(H,28,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Medical Research
Curated by ChEMBL
| Assay Description Inhibition of PTP1B |
J Med Chem 50: 2137-43 (2007)
Article DOI: 10.1021/jm061481l BindingDB Entry DOI: 10.7270/Q2BG2NP4 |
More data for this Ligand-Target Pair | |